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Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum
The human malaria parasite Plasmodium falciparum is responsible for the deaths of more than a million people each year. Fosmidomycin has been proven to be efficient in the treatment of P. falciparum malaria by inhibiting 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR), an enzyme of the non-mev...
Autores principales: | Umeda, Tomonobu, Tanaka, Nobutada, Kusakabe, Yoshio, Nakanishi, Masayuki, Kitade, Yukio, Nakamura, Kazuo T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216497/ https://www.ncbi.nlm.nih.gov/pubmed/22355528 http://dx.doi.org/10.1038/srep00009 |
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