Cargando…

Hyperthermic seizures and aberrant cellular homeostasis in Drosophila dystrophic muscles

In humans, mutations in the Dystrophin Glycoprotein Complex (DGC) cause muscular dystrophies (MDs) that are associated with muscle loss, seizures and brain abnormalities leading to early death. Using Drosophila as a model to study MD we have found that loss of Dystrophin (Dys) during development lea...

Descripción completa

Detalles Bibliográficos
Autores principales: Marrone, April K., Kucherenko, Mariya M., Wiek, Robert, Göpfert, Martin C., Shcherbata, Halyna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216534/
https://www.ncbi.nlm.nih.gov/pubmed/22355566
http://dx.doi.org/10.1038/srep00047