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Synergistic interactions between kainate and mGlu receptors regulate bouton Ca(2+) signalling and mossy fibre LTP

It is currently unknown why glutamatergic presynaptic terminals express multiple types of glutamate receptors. We have addressed this question by studying both acute and long-term regulation of mossy fibre function in the hippocampus. We find that inhibition of both mGlu(1) and mGlu(5) receptors tog...

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Detalles Bibliográficos
Autores principales: Nisticò, Robert, Dargan, Sheila L., Amici, Mascia, Collingridge, Graham L., Bortolotto, Zuner A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216588/
https://www.ncbi.nlm.nih.gov/pubmed/22355621
http://dx.doi.org/10.1038/srep00103