Polymeric human Fc-fusion proteins with modified effector functions

The success of Fc-fusion bio-therapeutics has spurred the development of other Fc-fusion products for treating and/or vaccinating against a range of diseases. We describe a method to modulate their function by converting them into well-defined stable polymers. This strategy resulted in cylindrical h...

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Detalles Bibliográficos
Autores principales: Mekhaiel, David N. A., Czajkowsky, Daniel M., Andersen, Jan Terje, Shi, Jianguo, El-Faham, Marwa, Doenhoff, Michael, McIntosh, Richard S., Sandlie, Inger, He, Jianfeng, Hu, Jun, Shao, Zhifeng, Pleass, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216605/
https://www.ncbi.nlm.nih.gov/pubmed/22355641
http://dx.doi.org/10.1038/srep00124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216605/
https://www.ncbi.nlm.nih.gov/pubmed/22355641
http://dx.doi.org/10.1038/srep00124

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