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A novel synthesis and detection method for cap-associated adenosine modifications in mouse mRNA

A method is described for the detection of certain nucleotide modifications adjacent to the 5' 7-methyl guanosine cap of mRNAs from individual genes. The method quantitatively measures the relative abundance of 2'-O-methyl and N(6),2'-O-dimethyladenosine, two of the most common modifi...

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Detalles Bibliográficos
Autores principales: Kruse, Susanne, Zhong, Silin, Bodi, Zsuzsanna, Button, James, Alcocer, Marcos J. C., Hayes, Christopher J., Fray, Rupert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216607/
https://www.ncbi.nlm.nih.gov/pubmed/22355643
http://dx.doi.org/10.1038/srep00126