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A novel synthesis and detection method for cap-associated adenosine modifications in mouse mRNA
A method is described for the detection of certain nucleotide modifications adjacent to the 5' 7-methyl guanosine cap of mRNAs from individual genes. The method quantitatively measures the relative abundance of 2'-O-methyl and N(6),2'-O-dimethyladenosine, two of the most common modifi...
Autores principales: | Kruse, Susanne, Zhong, Silin, Bodi, Zsuzsanna, Button, James, Alcocer, Marcos J. C., Hayes, Christopher J., Fray, Rupert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216607/ https://www.ncbi.nlm.nih.gov/pubmed/22355643 http://dx.doi.org/10.1038/srep00126 |
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