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p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment

The spindle assembly checkpoint links the onset of anaphase to completion of chromosome-microtubule attachment and is mediated by the binding of Mad and Bub proteins to kinetochores of unattached or maloriented chromosomes. Mad2 and BubR1 traffic between kinetochores and the cytosol, thereby transmi...

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Detalles Bibliográficos
Autores principales: Hagan, Robert S., Manak, Michael S., Buch, Håkon Kirkeby, Meier, Michelle G., Meraldi, Patrick, Shah, Jagesh V., Sorger, Peter K., Doxsey, Stephen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216650/
https://www.ncbi.nlm.nih.gov/pubmed/21965286
http://dx.doi.org/10.1091/mbc.E11-03-0216