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p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment
The spindle assembly checkpoint links the onset of anaphase to completion of chromosome-microtubule attachment and is mediated by the binding of Mad and Bub proteins to kinetochores of unattached or maloriented chromosomes. Mad2 and BubR1 traffic between kinetochores and the cytosol, thereby transmi...
Autores principales: | Hagan, Robert S., Manak, Michael S., Buch, Håkon Kirkeby, Meier, Michelle G., Meraldi, Patrick, Shah, Jagesh V., Sorger, Peter K., Doxsey, Stephen J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216650/ https://www.ncbi.nlm.nih.gov/pubmed/21965286 http://dx.doi.org/10.1091/mbc.E11-03-0216 |
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