The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress

Disruptions of the endoplasmic reticulum (ER) that perturb protein folding cause ER stress and elicit an unfolded protein response (UPR) that involves translational and transcriptional changes in gene expression aimed at expanding the ER processing capacity and alleviating cellular injury. Three ER...

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Detalles Bibliográficos
Autores principales: Teske, Brian F., Wek, Sheree A., Bunpo, Piyawan, Cundiff, Judy K., McClintick, Jeanette N., Anthony, Tracy G., Wek, Ronald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216664/
https://www.ncbi.nlm.nih.gov/pubmed/21917591
http://dx.doi.org/10.1091/mbc.E11-06-0510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216664/
https://www.ncbi.nlm.nih.gov/pubmed/21917591
http://dx.doi.org/10.1091/mbc.E11-06-0510

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