Expression of mutant TDP-43 induces neuronal dysfunction in transgenic mice

BACKGROUND: Abnormal distribution, modification and aggregation of transactivation response DNA-binding protein 43 (TDP-43) are the hallmarks of multiple neurodegenerative diseases, especially frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U) and amyotrophic lateral scler...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Ya-Fei, Zhang, Yong-Jie, Lin, Wen-Lang, Cao, Xiangkun, Stetler, Caroline, Dickson, Dennis W, Lewis, Jada, Petrucelli, Leonard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216869/
https://www.ncbi.nlm.nih.gov/pubmed/22029574
http://dx.doi.org/10.1186/1750-1326-6-73

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216869/
https://www.ncbi.nlm.nih.gov/pubmed/22029574
http://dx.doi.org/10.1186/1750-1326-6-73

Ejemplares similares