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Expression of mutant TDP-43 induces neuronal dysfunction in transgenic mice

BACKGROUND: Abnormal distribution, modification and aggregation of transactivation response DNA-binding protein 43 (TDP-43) are the hallmarks of multiple neurodegenerative diseases, especially frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U) and amyotrophic lateral scler...

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Detalles Bibliográficos
Autores principales:	Xu, Ya-Fei, Zhang, Yong-Jie, Lin, Wen-Lang, Cao, Xiangkun, Stetler, Caroline, Dickson, Dennis W, Lewis, Jada, Petrucelli, Leonard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216869/ https://www.ncbi.nlm.nih.gov/pubmed/22029574 http://dx.doi.org/10.1186/1750-1326-6-73

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