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Disordering of Human Telomeric G-Quadruplex with Novel Antiproliferative Anthrathiophenedione

Linear heteroareneanthracenediones have been shown to interfere with DNA functions, thereby causing death of human tumor cells and their drug resistant counterparts. Here we report the interaction of our novel antiproliferative agent 4,11-bis[(2-{[acetimido]amino}ethyl)amino]anthra[2,3-b]thiophene-5...

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Detalles Bibliográficos
Autores principales: Kaluzhny, Dmitry, Ilyinsky, Nikolay, Shchekotikhin, Andrei, Sinkevich, Yuri, Tsvetkov, Philipp O., Tsvetkov, Vladimir, Veselovsky, Alexander, Livshits, Mikhail, Borisova, Olga, Shtil, Alexander, Shchyolkina, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216923/
https://www.ncbi.nlm.nih.gov/pubmed/22102877
http://dx.doi.org/10.1371/journal.pone.0027151