Concentration-dependent Dual Effects of Hydrogen Peroxide on Insulin Signal Transduction in H4IIEC Hepatocytes

BACKGROUND: Oxidative stress induced by the accumulation of reactive oxygen species (ROS) has a causal role in the development of insulin resistance, whereas ROS themselves function as intracellular second messengers that promote insulin signal transduction. ROS can act both positively and negativel...

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Detalles Bibliográficos
Autores principales: Iwakami, Satoshi, Misu, Hirofumi, Takeda, Takashi, Sugimori, Makoto, Matsugo, Seiichi, Kaneko, Shuichi, Takamura, Toshinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216925/
https://www.ncbi.nlm.nih.gov/pubmed/22102892
http://dx.doi.org/10.1371/journal.pone.0027401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216925/
https://www.ncbi.nlm.nih.gov/pubmed/22102892
http://dx.doi.org/10.1371/journal.pone.0027401

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