Kallikreins 5, 6 and 10 Differentially Alter Pathophysiology and Overall Survival in an Ovarian Cancer Xenograft Model

Human tissue kallikreins (KLKs) are members of a multigene family of serine proteases aberrantly expressed in many cancer types. In ovarian cancer, 12 KLKs are upregulated, and of those KLK5, 6 and 10 have been the focus of investigations into new diagnostic and prognostic biomarkers. However, littl...

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Detalles Bibliográficos
Autores principales: Pépin, David, Shao, Zhong-Qi, Huppé, Geneviève, Wakefield, Andrea, Chu, Chee-Wui, Sharif, Zahra, Vanderhyden, Barbara C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216928/
https://www.ncbi.nlm.nih.gov/pubmed/22102857
http://dx.doi.org/10.1371/journal.pone.0026075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216928/
https://www.ncbi.nlm.nih.gov/pubmed/22102857
http://dx.doi.org/10.1371/journal.pone.0026075

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