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Kallikreins 5, 6 and 10 Differentially Alter Pathophysiology and Overall Survival in an Ovarian Cancer Xenograft Model
Human tissue kallikreins (KLKs) are members of a multigene family of serine proteases aberrantly expressed in many cancer types. In ovarian cancer, 12 KLKs are upregulated, and of those KLK5, 6 and 10 have been the focus of investigations into new diagnostic and prognostic biomarkers. However, littl...
Autores principales: | Pépin, David, Shao, Zhong-Qi, Huppé, Geneviève, Wakefield, Andrea, Chu, Chee-Wui, Sharif, Zahra, Vanderhyden, Barbara C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216928/ https://www.ncbi.nlm.nih.gov/pubmed/22102857 http://dx.doi.org/10.1371/journal.pone.0026075 |
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