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Chimeric Anti-Staphylococcal Enterotoxin B Antibodies and Lovastatin Act Synergistically to Provide In Vivo Protection against Lethal Doses of SEB

Staphylococcal enterotoxin B (SEB) is one of a family of toxins secreted by Staphylococcus aureus that act as superantigens, activating a large fraction of the T-cell population and inducing production of high levels of inflammatory cytokines that can cause toxic shock syndrome (TSS) and death. Extr...

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Detalles Bibliográficos
Autores principales: Tilahun, Mulualem E., Kwan, Alan, Natarajan, Kannan, Quinn, Megan, Tilahun, Ashenafi Y., Xie, Chen, Margulies, David H., Osborne, Barbara A., Goldsby, Richard A., Rajagopalan, Govindarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216929/
https://www.ncbi.nlm.nih.gov/pubmed/22102880
http://dx.doi.org/10.1371/journal.pone.0027203