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Chimeric Anti-Staphylococcal Enterotoxin B Antibodies and Lovastatin Act Synergistically to Provide In Vivo Protection against Lethal Doses of SEB
Staphylococcal enterotoxin B (SEB) is one of a family of toxins secreted by Staphylococcus aureus that act as superantigens, activating a large fraction of the T-cell population and inducing production of high levels of inflammatory cytokines that can cause toxic shock syndrome (TSS) and death. Extr...
Autores principales: | Tilahun, Mulualem E., Kwan, Alan, Natarajan, Kannan, Quinn, Megan, Tilahun, Ashenafi Y., Xie, Chen, Margulies, David H., Osborne, Barbara A., Goldsby, Richard A., Rajagopalan, Govindarajan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216929/ https://www.ncbi.nlm.nih.gov/pubmed/22102880 http://dx.doi.org/10.1371/journal.pone.0027203 |
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