Cargando…

M(5) Muscarinic Receptors Mediate Striatal Dopamine Activation by Ventral Tegmental Morphine and Pedunculopontine Stimulation in Mice

Opiates, like other addictive drugs, elevate forebrain dopamine levels and are thought to do so mainly by inhibiting GABA neurons near the ventral tegmental area (VTA), in turn leading to a disinhibition of dopamine neurons. However, cholinergic inputs from the laterodorsal (LDT) and pedunculopontin...

Descripción completa

Detalles Bibliográficos
Autores principales: Steidl, Stephan, Miller, Anthony D., Blaha, Charles D., Yeomans, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216953/
https://www.ncbi.nlm.nih.gov/pubmed/22102904
http://dx.doi.org/10.1371/journal.pone.0027538