Altered Islet Composition and Disproportionate Loss of Large Islets in Patients with Type 2 Diabetes

Human islets exhibit distinct islet architecture with intermingled alpha- and beta-cells particularly in large islets. In this study, we quantitatively examined pathological changes of the pancreas in patients with type 2 diabetes (T2D). Specifically, we tested a hypothesis that changes in endocrine...

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Detalles Bibliográficos
Autores principales: Kilimnik, German, Zhao, Billy, Jo, Junghyo, Periwal, Vipul, Witkowski, Piotr, Misawa, Ryosuke, Hara, Manami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216964/
https://www.ncbi.nlm.nih.gov/pubmed/22102895
http://dx.doi.org/10.1371/journal.pone.0027445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216964/
https://www.ncbi.nlm.nih.gov/pubmed/22102895
http://dx.doi.org/10.1371/journal.pone.0027445

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