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S6K1 and 4E-BP1 Are Independent Regulated and Control Cellular Growth in Bladder Cancer

Aberrant activation and mutation status of proteins in the phosphatidylinositol-3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) and the mitogen activated protein kinase (MAPK) signaling pathways have been linked to tumorigenesis in various tumors including urothelial carcinoma (UC). However...

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Detalles Bibliográficos
Autores principales: Nawroth, Roman, Stellwagen, Florian, Schulz, Wolfgang A., Stoehr, Robert, Hartmann, Arndt, Krause, Bernd J., Gschwend, Juergen E., Retz, Margitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216974/
https://www.ncbi.nlm.nih.gov/pubmed/22110663
http://dx.doi.org/10.1371/journal.pone.0027509