Mitochondrial DNA Haplogroup Background Affects LHON, but Not Suspected LHON, in Chinese Patients

Recent studies have shown that mtDNA background could affect the clinical expression of Leber hereditary optic neuropathy (LHON). We analyzed the mitochondrial DNA (mtDNA) variation of 304 Chinese patients with m.11778G>A (sample #1) and of 843 suspected LHON patients who lack the three primary m...

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Detalles Bibliográficos
Autores principales: Zhang, A-Mei, Jia, Xiaoyun, Bi, Rui, Salas, Antonio, Li, Shiqiang, Xiao, Xueshan, Wang, Panfeng, Guo, Xiangming, Kong, Qing-Peng, Zhang, Qingjiong, Yao, Yong-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216987/
https://www.ncbi.nlm.nih.gov/pubmed/22110754
http://dx.doi.org/10.1371/journal.pone.0027750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216987/
https://www.ncbi.nlm.nih.gov/pubmed/22110754
http://dx.doi.org/10.1371/journal.pone.0027750

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