Inactivation of SAG E3 Ubiquitin Ligase Blocks Embryonic Stem Cell Differentiation and Sensitizes Leukemia Cells to Retinoid Acid

Sensitive to Apoptosis Gene (SAG), also known as RBX2 (RING box protein-2), is the RING component of SCF (SKP1, Cullin, and F-box protein) E3 ubiquitin ligase. Our previous studies have demonstrated that SAG is an anti-apoptotic protein and an attractive anti-cancer target. We also found recently th...

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Detalles Bibliográficos
Autores principales: Tan, Mingjia, Li, Yun, Yang, Ruiguo, Xi, Ning, Sun, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217012/
https://www.ncbi.nlm.nih.gov/pubmed/22110742
http://dx.doi.org/10.1371/journal.pone.0027726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217012/
https://www.ncbi.nlm.nih.gov/pubmed/22110742
http://dx.doi.org/10.1371/journal.pone.0027726

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