Increased 90-kDa ribosomal S6 kinase (Rsk) activity is protective against mutant huntingtin toxicity

BACKGROUND: The 90-kDa ribosomal S6 kinase (Rsk) family is involved in cell survival. Rsk activation is regulated by sequential phosphorylations controlled by extracellular signal-regulated kinase (ERK) 1/2 and 3-phosphoinositide-dependent protein kinase 1 (PDK1). Altered ERK1/2 and PDK1 phosphoryla...

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Detalles Bibliográficos
Autores principales: Xifró, Xavier, Anglada-Huguet, Marta, Rué, Laura, Saavedra, Ana, Pérez-Navarro, Esther, Alberch, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217046/
https://www.ncbi.nlm.nih.gov/pubmed/22041125
http://dx.doi.org/10.1186/1750-1326-6-74

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217046/
https://www.ncbi.nlm.nih.gov/pubmed/22041125
http://dx.doi.org/10.1186/1750-1326-6-74

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