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GILT modulates CD4(+) T cell tolerance to the melanocyte differentiation antigen tyrosinase-related protein 1

Gamma-interferon-inducible lysosomal thiol reductase (GILT) facilitates MHC class II-restricted processing though endocytic reduction of protein disulfide bonds and is necessary for efficient class II-restricted processing of melanocyte differentiation antigen, tyrosinase-related protein 1 (TRP1). U...

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Detalles Bibliográficos
Autores principales: Rausch, Matthew P., Hastings, Karen Taraszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217059/
https://www.ncbi.nlm.nih.gov/pubmed/21833020
http://dx.doi.org/10.1038/jid.2011.236