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Integrated genomic approaches to identification of candidate genes underlying metabolic and cardiovascular phenotypes in the spontaneously hypertensive rat

The spontaneously hypertensive rat (SHR) is a widely used rodent model of hypertension and metabolic syndrome. Previously we identified thousands of cis-regulated expression quantitative trait loci (eQTLs) across multiple tissues using a panel of rat recombinant inbred (RI) strains derived from Brow...

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Detalles Bibliográficos
Autores principales: Morrissey, Catherine, Grieve, Ian C., Heinig, Matthias, Atanur, Santosh, Petretto, Enrico, Pravenec, Michal, Hubner, Norbert, Aitman, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217321/
https://www.ncbi.nlm.nih.gov/pubmed/21846806
http://dx.doi.org/10.1152/physiolgenomics.00210.2010