Real-Time G-Protein-Coupled Receptor Imaging to Understand and Quantify Receptor Dynamics

Understanding the trafficking of G-protein-coupled receptors (GPCRs) and their regulation by agonists and antagonists is fundamental to develop more effective drugs. Optical methods using fluorescent-tagged receptors and spinning disk confocal microscopy are useful tools to investigate membrane rece...

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Detalles Bibliográficos
Autores principales: Aymerich, María S., López-Azcárate, J., Bonaventura, J., Navarro, G., Fernández-Suárez, D., Casadó, V., Mayor, F., Lluís, C., Valencia, M., Artieda, J., Franco, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217607/
https://www.ncbi.nlm.nih.gov/pubmed/22125451
http://dx.doi.org/10.1100/2011/690858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217607/
https://www.ncbi.nlm.nih.gov/pubmed/22125451
http://dx.doi.org/10.1100/2011/690858

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