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Real-Time G-Protein-Coupled Receptor Imaging to Understand and Quantify Receptor Dynamics
Understanding the trafficking of G-protein-coupled receptors (GPCRs) and their regulation by agonists and antagonists is fundamental to develop more effective drugs. Optical methods using fluorescent-tagged receptors and spinning disk confocal microscopy are useful tools to investigate membrane rece...
Autores principales: | Aymerich, María S., López-Azcárate, J., Bonaventura, J., Navarro, G., Fernández-Suárez, D., Casadó, V., Mayor, F., Lluís, C., Valencia, M., Artieda, J., Franco, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
TheScientificWorldJOURNAL
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217607/ https://www.ncbi.nlm.nih.gov/pubmed/22125451 http://dx.doi.org/10.1100/2011/690858 |
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