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Protein phosphatase 2a (PP2A) binds within the oligomerization domain of striatin and regulates the phosphorylation and activation of the mammalian Ste20-Like kinase Mst3

BACKGROUND: Striatin, a putative protein phosphatase 2A (PP2A) B-type regulatory subunit, is a multi-domain scaffolding protein that has recently been linked to several diseases including cerebral cavernous malformation (CCM), which causes symptoms ranging from headaches to stroke. Striatin associat...

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Detalles Bibliográficos
Autores principales: Gordon, Johnthan, Hwang, Juyeon, Carrier, Karma J, Jones, Candace A, Kern, Quiana L, Moreno, Carlos S, Karas, Richard H, Pallas, David C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217859/
https://www.ncbi.nlm.nih.gov/pubmed/21985334
http://dx.doi.org/10.1186/1471-2091-12-54