Resveratrol enhances prostate cancer cell response to ionizing radiation. Modulation of the AMPK, Akt and mTOR pathways

BACKGROUND: Prostate cancer (PrCa) displays resistance to radiotherapy (RT) and requires radiotherapy dose escalation which is associated with greater toxicity. This highlights a need to develop radiation sensitizers to improve the efficacy of RT in PrCa. Ionizing radiation (IR) stimulates pathways...

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Detalles Bibliográficos
Autores principales: Rashid, Ayesha, Liu, Caiqiong, Sanli, Toran, Tsiani, Evangelia, Singh, Gurmit, Bristow, Robert G, Dayes, Ian, Lukka, Himu, Wright, James, Tsakiridis, Theodoros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217881/
https://www.ncbi.nlm.nih.gov/pubmed/22029423
http://dx.doi.org/10.1186/1748-717X-6-144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217881/
https://www.ncbi.nlm.nih.gov/pubmed/22029423
http://dx.doi.org/10.1186/1748-717X-6-144

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