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Can Linear Regression Modeling Help Clinicians in the Interpretation of Genotypic Resistance Data? An Application to Derive a Lopinavir-Score

BACKGROUND: The question of whether a score for a specific antiretroviral (e.g. lopinavir/r in this analysis) that improves prediction of viral load response given by existing expert-based interpretation systems (IS) could be derived from analyzing the correlation between genotypic data and virologi...

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Detalles Bibliográficos
Autores principales: Cozzi-Lepri, Alessandro, Prosperi, Mattia C. F., Kjær, Jesper, Dunn, David, Paredes, Roger, Sabin, Caroline A., Lundgren, Jens D., Phillips, Andrew N., Pillay, Deenan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217925/
https://www.ncbi.nlm.nih.gov/pubmed/22110581
http://dx.doi.org/10.1371/journal.pone.0025665