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Optimal Deconvolution of Transcriptional Profiling Data Using Quadratic Programming with Application to Complex Clinical Blood Samples

Large-scale molecular profiling technologies have assisted the identification of disease biomarkers and facilitated the basic understanding of cellular processes. However, samples collected from human subjects in clinical trials possess a level of complexity, arising from multiple cell types, that c...

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Detalles Bibliográficos
Autores principales: Gong, Ting, Hartmann, Nicole, Kohane, Isaac S., Brinkmann, Volker, Staedtler, Frank, Letzkus, Martin, Bongiovanni, Sandrine, Szustakowski, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217948/
https://www.ncbi.nlm.nih.gov/pubmed/22110609
http://dx.doi.org/10.1371/journal.pone.0027156