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Optimal Deconvolution of Transcriptional Profiling Data Using Quadratic Programming with Application to Complex Clinical Blood Samples
Large-scale molecular profiling technologies have assisted the identification of disease biomarkers and facilitated the basic understanding of cellular processes. However, samples collected from human subjects in clinical trials possess a level of complexity, arising from multiple cell types, that c...
Autores principales: | Gong, Ting, Hartmann, Nicole, Kohane, Isaac S., Brinkmann, Volker, Staedtler, Frank, Letzkus, Martin, Bongiovanni, Sandrine, Szustakowski, Joseph D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217948/ https://www.ncbi.nlm.nih.gov/pubmed/22110609 http://dx.doi.org/10.1371/journal.pone.0027156 |
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