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Paternal Cyclophosphamide Exposure Induces the Formation of Functional Micronuclei during the First Zygotic Division

Paternal exposures to cancer chemotherapeutics or environmental chemicals may have adverse effects on progeny outcome that are manifested in the preimplantation embryo. The objectives of this study were to determine the impact of paternal exposure to cyclophosphamide, an anticancer alkylating agent,...

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Detalles Bibliográficos
Autores principales: Grenier, Lisanne, Robaire, Bernard, Hales, Barbara F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217984/
https://www.ncbi.nlm.nih.gov/pubmed/22110683
http://dx.doi.org/10.1371/journal.pone.0027600