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Tumor-Derived G-CSF Facilitates Neoplastic Growth through a Granulocytic Myeloid-Derived Suppressor Cell-Dependent Mechanism

Myeloid-derived suppressor cells (MDSC) are induced under diverse pathologic conditions, including neoplasia, and suppress innate and adaptive immunity. While the mechanisms by which MDSC mediate immunosuppression are well-characterized, details on how they develop remain less understood. This is co...

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Detalles Bibliográficos
Autores principales: Waight, Jeremy D., Hu, Qiang, Miller, Austin, Liu, Song, Abrams, Scott I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218014/
https://www.ncbi.nlm.nih.gov/pubmed/22110722
http://dx.doi.org/10.1371/journal.pone.0027690