Design, Synthesis, and Pharmacological Evaluation of Haloperidol Derivatives as Novel Potent Calcium Channel Blockers with Vasodilator Activity

Several haloperidol derivatives with a piperidine scaffold that was decorated at the nitrogen atom with different alkyl, benzyl, or substituted benzyl moieties were synthesized at our laboratory to establish a library of compounds with vasodilator activity. Compounds were screened for vasodilatory a...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yicun, Zheng, Jinhong, Zheng, Fuchun, Wang, Jinzhi, Zhang, Yanmei, Gao, Fenfei, Huang, Zhanqin, Shi, Ganggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218019/
https://www.ncbi.nlm.nih.gov/pubmed/22110716
http://dx.doi.org/10.1371/journal.pone.0027673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218019/
https://www.ncbi.nlm.nih.gov/pubmed/22110716
http://dx.doi.org/10.1371/journal.pone.0027673

Ejemplares similares