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Design, Synthesis, and Pharmacological Evaluation of Haloperidol Derivatives as Novel Potent Calcium Channel Blockers with Vasodilator Activity

Several haloperidol derivatives with a piperidine scaffold that was decorated at the nitrogen atom with different alkyl, benzyl, or substituted benzyl moieties were synthesized at our laboratory to establish a library of compounds with vasodilator activity. Compounds were screened for vasodilatory a...

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Detalles Bibliográficos
Autores principales:	Chen, Yicun, Zheng, Jinhong, Zheng, Fuchun, Wang, Jinzhi, Zhang, Yanmei, Gao, Fenfei, Huang, Zhanqin, Shi, Ganggang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218019/ https://www.ncbi.nlm.nih.gov/pubmed/22110716 http://dx.doi.org/10.1371/journal.pone.0027673

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