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Inhaled Nitric Oxide Reduces Endothelial Activation and Parasite Accumulation in the Brain, and Enhances Survival in Experimental Cerebral Malaria

The host immune response contributes to the onset and progression of severe malaria syndromes, such as cerebral malaria. Adjunctive immunomodulatory strategies for severe malaria may improve clinical outcome beyond that achievable with artemisinin-based therapy alone. Here, we report that prophylaxi...

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Detalles Bibliográficos
Autores principales: Serghides, Lena, Kim, Hani, Lu, Ziyue, Kain, Dylan C., Miller, Chris, Francis, Roland C., Liles, W. Conrad, Zapol, Warren M., Kain, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218025/
https://www.ncbi.nlm.nih.gov/pubmed/22110737
http://dx.doi.org/10.1371/journal.pone.0027714