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Inhibitory Role of Notch1 in Calcific Aortic Valve Disease

Aortic valve calcification is the most common form of valvular heart disease, but the mechanisms of calcific aortic valve disease (CAVD) are unknown. NOTCH1 mutations are associated with aortic valve malformations and adult-onset calcification in families with inherited disease. The Notch signaling...

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Detalles Bibliográficos
Autores principales: Acharya, Asha, Hans, Chetan P., Koenig, Sara N., Nichols, Haley A., Galindo, Cristi L., Garner, Harold R., Merrill, Walter H., Hinton, Robert B., Garg, Vidu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218038/
https://www.ncbi.nlm.nih.gov/pubmed/22110751
http://dx.doi.org/10.1371/journal.pone.0027743