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Modeling the Basal Dynamics of P53 System

BACKGROUND: The tumor suppressor p53 has become one of most investigated genes. Once activated by stress, p53 leads to cellular responses such as cell cycle arrest and apoptosis. METHODOLOGY/PRINCIPAL FINDINGS: Most previous models have ignored the basal dynamics of p53 under nonstressed conditions....

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Detalles Bibliográficos
Autores principales: Sun, Tingzhe, Yang, Weiwei, Liu, Jing, Shen, Pingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218058/
https://www.ncbi.nlm.nih.gov/pubmed/22114721
http://dx.doi.org/10.1371/journal.pone.0027882