Ribavirin Enhances IFN-α Signalling and MxA Expression: A Novel Immune Modulation Mechanism during Treatment of HCV

The nucleoside analogue Ribavirin significantly increases patient response to IFN-α treatment of HCV, by directly inhibiting viral replication. Recent studies indicate that Ribavirin also regulates immunity and we propose that Ribavirin enhances specific interferon sensitive gene (ISG) expression by...

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Detalles Bibliográficos
Autores principales: Stevenson, Nigel J., Murphy, Alison G., Bourke, Nollaig M., Keogh, Catherine A., Hegarty, John E., O'Farrelly, Cliona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218071/
https://www.ncbi.nlm.nih.gov/pubmed/22114715
http://dx.doi.org/10.1371/journal.pone.0027866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218071/
https://www.ncbi.nlm.nih.gov/pubmed/22114715
http://dx.doi.org/10.1371/journal.pone.0027866

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