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α-ketoglutarate coordinates carbon and nitrogen utilization via Enzyme I inhibition

Microbes survive in a variety of nutrient environments by modulating their intracellular metabolism. Balanced growth requires coordinated uptake of carbon and nitrogen, the primary substrates for biomass production. The mechanisms that balance carbon and nitrogen uptake are, however, poorly understo...

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Detalles Bibliográficos
Autores principales: Doucette, Christopher D, Schwab, David J, Wingreen, Ned S, Rabinowitz, Joshua D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218208/
https://www.ncbi.nlm.nih.gov/pubmed/22002719
http://dx.doi.org/10.1038/nchembio.685