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GPCRs regulate the assembly of a multienzyme complex for purine biosynthesis

G protein-coupled receptors (GPCRs) transmit exogenous signals to the nucleus, promoting a myriad of biological responses via multiple signaling pathways in both normal and cancer cells. However, little is known about the response in cytosolic metabolic pathways to GPCR-mediated signaling. Here, we...

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Detalles Bibliográficos
Autores principales: Verrier, Florence, An, Songon, Ferrie, Ann M., Sun, Haiyan, Kyoung, Minjoung, Deng, Huayun, Fang, Ye, Benkovic, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218230/
https://www.ncbi.nlm.nih.gov/pubmed/22020552
http://dx.doi.org/10.1038/nchembio.690