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Promotion of cytoplasmic mislocalization of p27 by Helicobacter pylori in gastric cancer

The cyclin-dependent kinase inhibitor p27 plays an important role in cell cycle regulation. Reduced expression of p27 is commonly associated with poor prognosis in many malignancies, including gastric cancer. Cytoplasmic p27 mislocalization may be an additional indicator of high-grade tumors and poo...

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Detalles Bibliográficos
Autores principales: Wen, Sicheng, So, Yoshiya, Singh, Kamaljeet, Slingerland, Joyce M., Resnick, Murray B., Zhang, Songhua, Ruiz, Victoria, Moss, Steven F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218262/
https://www.ncbi.nlm.nih.gov/pubmed/21841827
http://dx.doi.org/10.1038/onc.2011.362