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Molecular modeling and identification of substrate binding site of orphan human cytochrome P450 4F22
Cytochrome P450s are superfamily of heme proteins which generally monooxygenate hydrophobic compounds. The human cytochrome P450 4F22 (CYP4F22) was categorized into “orphan” CYPs because of its unknown function. CYP4F22 is a potential drug target for cancer therapy. However, three-dimensional struct...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Biomedical Informatics
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218523/ https://www.ncbi.nlm.nih.gov/pubmed/22102778 |