Uptake and intracellular traffic of siRNA dendriplexes in glioblastoma cells and macrophages

BACKGROUND: Gene silencing using small interfering RNA (siRNA) is a promising new therapeutic approach for glioblastoma. The endocytic uptake and delivery of siRNA to intracellular compartments could be enhanced by complexation with polyamidoamine dendrimers. In the present work, the uptake mechanis...

Descripción completa

Detalles Bibliográficos
Autores principales: Perez, Ana Paula, Cosaka, Maria Luz, Romero, Eder Lilia, Morilla, Maria Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218585/
https://www.ncbi.nlm.nih.gov/pubmed/22114502
http://dx.doi.org/10.2147/IJN.S25235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218585/
https://www.ncbi.nlm.nih.gov/pubmed/22114502
http://dx.doi.org/10.2147/IJN.S25235

Ejemplares similares