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Detecting sequence polymorphisms associated with meiotic recombination hotspots in the human genome

BACKGROUND: Meiotic recombination events tend to cluster into narrow spans of a few kilobases long, called recombination hotspots. Such hotspots are not conserved between human and chimpanzee and vary between different human ethnic groups. At the same time, recombination hotspots are heritable. Prev...

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Detalles Bibliográficos
Autores principales: Zheng, Jie, Khil, Pavel P, Camerini-Otero, R Daniel, Przytycka, Teresa M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218659/
https://www.ncbi.nlm.nih.gov/pubmed/20961408
http://dx.doi.org/10.1186/gb-2010-11-10-r103