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The role of the NLRP3 inflammasome in gout

Gout is an inflammatory arthritis characterized by abrupt self-limiting attacks of inflammation caused by precipitation of monosodium urate crystals (MSU) in the joint. Recent studies suggest that orchestration of the MSU-induced inflammatory response is dependent on the proinflammatory cytokine IL-...

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Detalles Bibliográficos
Autores principales: Kingsbury, Sarah R, Conaghan, Philip G, McDermott, Michael F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218743/
https://www.ncbi.nlm.nih.gov/pubmed/22096368
http://dx.doi.org/10.2147/JIR.S11330