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A comparative analysis of DNA methylation across human embryonic stem cell lines

BACKGROUND: We performed a comparative analysis of the genome-wide DNA methylation profiles from three human embryonic stem cell (HESC) lines. It had previously been shown that HESC lines had significantly higher non-CG methylation than differentiated cells, and we therefore asked whether these site...

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Detalles Bibliográficos
Autores principales: Chen, Pao-Yang, Feng, Suhua, Joo, Jong Wha Joanne, Jacobsen, Steve E, Pellegrini, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218824/
https://www.ncbi.nlm.nih.gov/pubmed/21733148
http://dx.doi.org/10.1186/gb-2011-12-7-r62