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Proteome-wide evidence for enhanced positive Darwinian selection within intrinsically disordered regions in proteins

BACKGROUND: Understanding the adaptive changes that alter the function of proteins during evolution is an important question for biology and medicine. The increasing number of completely sequenced genomes from closely related organisms, as well as individuals within species, facilitates systematic d...

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Detalles Bibliográficos
Autores principales: Nilsson, Johan, Grahn, Mats, Wright, Anthony PH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218827/
https://www.ncbi.nlm.nih.gov/pubmed/21771306
http://dx.doi.org/10.1186/gb-2011-12-7-r65