Substitution rate variation at human CpG sites correlates with non-CpG divergence, methylation level and GC content

BACKGROUND: A major goal in the study of molecular evolution is to unravel the mechanisms that induce variation in the germ line mutation rate and in the genome-wide mutation profile. The rate of germ line mutation is considerably higher for cytosines at CpG sites than for any other nucleotide in th...

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Detalles Bibliográficos
Autores principales: Mugal, Carina F, Ellegren, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218846/
https://www.ncbi.nlm.nih.gov/pubmed/21696599
http://dx.doi.org/10.1186/gb-2011-12-6-r58

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218846/
https://www.ncbi.nlm.nih.gov/pubmed/21696599
http://dx.doi.org/10.1186/gb-2011-12-6-r58

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